Dual impact from coincide potential complications of cancer therapy and sarcopenia: a narrative review

Sarcopenia is a disorder of progressive loss skeletal muscle mass and strength that linked with multiple complications, decreased physical activity, lower quality life accelerated mortality rate. It more common among cancer patients identified reduced tolerance by the toxic effects from therapy, negative outcomes, lowered response overall survival This narrative review aims to demonstrate dual impact co-occurrence therapy; chemotherapy, radiotherapy, immunotherapy, sarcopenia alongside potential complications their coincide on prognosis. By searching through data sets, all articles focused therapy were collected in indexed journals between years 2000 2021 could provide findings for coinciding receiving chemo-radio- immunotherapy. Outcome measures rate studies showing therapies sarcopenia. A total hundred-two cohort enrolled. The majority about chemotherapy (45%). About 56.9% designed as retrospective analysis, high proportion (21.6%). 63.7% reported index primary marker. Lower than half reviewed revealed significant increase (47%). direct 13.7% studies. Studies reduction cycles 10.8%. 11.8% 14.7% showed chemotherapy/radiotherapy sarcopenia, respectively. In conclusion, evaluation should be considered part oncological care there are poor different therapies.